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HemoShear to Develop Human Cancer Models

Thursday, November 07, 2013  
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Safer and more effective anticancer drugs may soon be developed thanks to a Small Business Innovation Research (SBIR) contract recently awarded to HemoShear by the National Cancer Institute (NCI) of the U.S. National Institutes of Health (NIH). HemoShear, LLC, located in Charlottesville, is a developer of advanced human biology systems for applications in drug research and development.


Anticancer drugs continue to suffer the highest rate of failure in clinical trials as compared with other therapeutic areas. HemoShear's contract with the National Cancer Institute will support the development of human cell-based systems that replicate the biology of lung and pancreatic tumors, two of the deadliest groups of tumors.


"Lung and pancreatic cancer are terrible diseases that have no effective treatments," said Dr. Brian Wamhoff, HemoShear co-founder and Vice President of R&D. "We are using our innovative science to enable the discovery of new treatments for cancer patients. While billions of dollars continue to be spent on researching and developing new cancer therapies, their success rates in clinical trials are not improving. Imagine a human tumor on the laboratory bench that responds to new therapies as if it were in the human body. That is what our science is capable of achieving," he continued.


HemoShear's success in this initial stage of tumor system development will lead to development of other cancer tumor systems, to systems that replicate metastasis and potentially to new treatments for patient-specific tumors.


"This is HemoShear's third major area of SBIR funding from separate divisions of the NIH in three years. We are grateful for the strong support of NIH and the scientific community. We believe that HemoShear science will yield safer and more effective therapies while avoiding costly new drug failures," said Jim Powers, HemoShear's CEO.

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