News

Serpin Pharma Secures $2 Million NCI Grant for Innovative Neuropathy Treatment

Serpin Pharma, a Virginia-based biopharmaceutical company, is proud to announce that it has been awarded a $2 million Phase II Small Business Innovation Research (SBIR) grant from the National Cancer Institute (NCI).

This grant will support the clinical development of SP16-3M, a groundbreaking peptide drug designed to prevent chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients.

Collaborative Clinical Trial

The funding will facilitate a collaborative clinical trial led by Dr. Patrick Dillon at the University of Virginia. The trial aims to evaluate the efficacy of SP16-3M in:

– Protecting nerves from chemotherapy-induced toxicity

– Facilitating nerve repair

– Alleviating pain for breast cancer patients undergoing treatment

Addressing a Critical Need

CIPN is a common and often debilitating side effect of cancer treatment that can significantly impact patients’ quality of life. SP163M represents a potential breakthrough in managing this condition. By preventing neuropathy, SP163M could enable patients to complete their full chemotherapy regimens without dose reductions, potentially improving overall cancer treatment outcomes.

Expert Insights

Dr. Patrick Dillon expressed his enthusiasm for the collaboration: “I am excited about this partnership, as both UVA and Serpin are dedicated to finding solutions for treatment-induced neuropathy in cancer patients.”

Dr. Cohava Gelber, Founder and CEO of Serpin Pharma, also shared her thoughts: “We are thrilled to work with Dr. Dillon and UVA to bring the promise of our groundbreaking drug to breast cancer patients, aiming to prevent their suffering from debilitating pain after chemotherapy.”

Looking Ahead
The NCI award highlights the significant potential of SP163M in addressing a critical unmet need in cancer care. As Serpin Pharma advances its clinical development efforts, breast cancer patients may soon have access to this innovative therapy, enhancing their quality of life during and after chemotherapy.

 

Learn more here.

Recent News

02/17/2026

Serpin Pharma, Inc. Announces Approval to Initiate EASE‑AKI Phase II Clinical Trial in Germany

Serpin Pharma, Inc., a clinical‑stage biopharmaceutical company developing first‑in‑class LRP1‑agonist therapeutics, today announced that its Phase II clinical trial, EASE-AKI, has received unconditional approval to begin enrolling patients in Germany. The study will evaluate SP16, a powerful yet well-tolerated anti-inflammatory peptide, designed to protect the kidneys of patients with chronic kidney disease who are undergoing

02/09/2026

Activation Capital Expands Frontier BioHealth and Strengthens its Continuum of Support for Life Sciences Founders

Activation Capital today announced enhancements to Frontier BioHealth, building on the program’s successful 2024 launch and inaugural cohort while reinforcing its broader continuum of life sciences entrepreneurship programs designed to help science-driven companies progress toward commercialization and investor readiness. Frontier BioHealth was created to address a critical gap facing emerging biohealth founders: access to practical

02/04/2026

Governor Spanberger Announces Expansion of Paid Internship Opportunities with Virginia Businesses

Governor Abigail Spanberger today launched InternshipsVA, a new statewide program to help Virginia employers design and launch high-quality, paid internships for higher education students in Virginia. The Commonwealth has committed $14.5 million each year to support this program. The Governor was joined by leaders of the Virginia Chamber of Commerce, the Virginia Economic Development Partnership